Palmerolide 是什么？有何作用？

Palmerolide A, a 20-membered macrocyclic polyketide bearing carbamate and vinyl amide functionality, was isolated from the tunicate Synoicum adareanum collected from the vicinity of Palmer Station on the Antarctic Peninsula. Palmerolide A displays potent and selective cytotoxicity toward melanoma (UACC-66 LC50 = 0.018 M) and appears to operate via inhibition (IC50 = 2 nM) of V-ATPase.

帕默内酯A 一种由20个成员组成的一类大环聚酮类抗生素，它含有氨基甲酸盐和乙烯氨基等官能团，它是从南极半岛帕默站附近分离的有包膜的Synoicum adareanum中分离的。它对恶性黑痣瘤等具有强烈的细胞毒作用，它是通过抑制V型ATP酶的活性来杀死细胞的。

翻译得不地道，将就着看吧！

我也不懂，你看一下是不是这个。
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