关于Atherton-Todd反应谁能给我个详细介绍啊
来源:百度知道 编辑:UC知道 时间:2024/06/05 09:01:25
Atherton-Todd reaction is a useful synthetic
approach. It involves the oxidation of dialkyl phosphonates with
chlorocarbons into dialkyl or trialkyl phosphates under mild
conditions. The versatility of the reaction results from the fact
that the initial products in the reaction are the highly reactive
dialkyl chlorophosphates (eq I), which in the presence of amines
RO-PHO-OR + CC14 -base-> RO-PClO-OR + CHC13
or alcohols are converted in situ into the corresponding dialkyl
phosphoramides or trialkyl phosphates, respectively.