how to do with it 对不对

绝对没问题 我听美国人这么说过

这个等于=how to deal with it

对，do with的意思是忍受，处理，控制等。
How to do sth是一个固定用法，意思是怎样做...
How to do with it，看情况可以翻译成许多意思：怎样控制它；怎样处理它；怎样容忍它；等

what to do with

how to deal with

中文式英语吧！

应该是how to fix/deal with it

不对 how to deal with it =what to do with it

当然不对了
how to deal with it =what to do with 处理...