哥哥你怎么了？用英语怎么说

What's wrong with you,brother?

what's the matter with you, my brother?

What's the matter with you,brother? 或着What's wrong with you,brother?

what`s`wrong with you ,my brother?
哥哥你怎么了？

这句话肯定是你问你的哥哥，所以要这样说

书面语：
what about you，brother？
What's wrong with you,brother?
口语：
brother what about you？
brother What's wrong with you？

A brother, how can you?