先生，请问要喝点什么？怎么翻译？

我觉得what would you like to drink,sir是最佳

What would you like for/to drink, sir?

Could I get you some drink, sir?

在国外的店里好象就那么随便的一句吧
Can I help you,sir?......不信大家可以来国外亲身体验下...
不过中国式批改的话,不搭上点drink之类的词,我估计肯定都不会算对,呵呵.

sir,would you like something to drink?

What would you like to drink, Sir?

Care for a drink,sir?