there are five people at my home,they are my parents and i 还是they are my parents and me

我觉得这句话可以写成
There are five person in my family, my grandparents, my parents and me

如果一定要用你给的there are ．．．, they are 句式，应该将逗号改句号
即 There are five people at my home．They are my grandparents, my parents and me.

分两种情况，在规范的语法当中，应该是they are my grandparents my parents and i，如果要说me， 应该是they are me， my grandparents and my parents.

你给的分好高啊！
I和me都是代词，但me 是用作宾格。如Give me a drink.给我一杯饮料。
所以是……and me

应该是they are my grandparents my parents and me
这里用宾格是正确的

there are five people at my home,they are my parents and i 还是they are my parents and me

最好把at my home 改成in my home.
逗号要改句号。
一般书面语要用me.