UC知道在线等翻译.关于高分子材料的毕业论文.急急急～～～～～
来源：百度知道 编辑：UC知道 时间：2024/05/21 18:59:24
CPNHA
Fig. 1. Chemical reaction scheme for synthesizing CPN and CPNHA.
Please cite this article in press as: J.-Y. Fang et al., Temperature-sensitive hydrogels composed of chitosan and ..., Eur. J. Pharm.
Biopharm. (2007), doi:10.1016/j.ejpb.2007.08.012
ARTICLEINPRESSARTICLEINPRESS
J.-Y. Fang et al./European Journal of Pharmaceutics and Biopharmaceutics xxx (2007) xxx–xxx
vacuum-dried, dissolved in acetone, and precipitated by
dropwise addition into an ether solution. After being filtered
and dried, the polymer was dialyzed against double-
distilled water for 7d (Sepectra/Por3, MW cut-off
3500 Da) and then freeze-dried in order to obtain the
polymer.
2.2.2. CPN synthesis
PNIPAAm (10 g) and chitosan (1 g) were dissolved in
100 ml of 0.1MMES (pH 5.0).EDCand NHS were added
to the above solution. The stoichiometric ratio of ACOOH
in PNIPAAm-COOH/EDC/NHS was 1:10:50.
Fig. 1. Chemical reaction scheme for synthesizing CPN and CPNHA.
Please cite this article in press as: J.-Y. Fang et al., Temperature-sensitive hydrogels composed of chitosan and ..., Eur. J. Pharm.
Biopharm. (2007), doi:10.1016/j.ejpb.2007.08.012
ARTICLEINPRESSARTICLEINPRESS
J.-Y. Fang et al./European Journal of Pharmaceutics and Biopharmaceutics xxx (2007) xxx–xxx
vacuum-dried, dissolved in acetone, and precipitated by
dropwise addition into an ether solution. After being filtered
and dried, the polymer was dialyzed against double-
distilled water for 7d (Sepectra/Por3, MW cut-off
3500 Da) and then freeze-dried in order to obtain the
polymer.
2.2.2. CPN synthesis
PNIPAAm (10 g) and chitosan (1 g) were dissolved in
100 ml of 0.1MMES (pH 5.0).EDCand NHS were added
to the above solution. The stoichiometric ratio of ACOOH
in PNIPAAm-COOH/EDC/NHS was 1:10:50.
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