Hunig’s base是什么

来源:百度知道 编辑:UC知道 时间:2024/06/21 15:42:46
化学达人来指点一下啊

N,N-Diisopropylethylamine, or Hünig's base, DIPEA or DIEA, is an organic compound and an amine. It is used in organic chemistry as a base. Because the nitrogen atom is shielded by the two isopropyl groups and an ethyl group only a proton is small enough to easily fit. Just like 2,2,6,6-tetramethylpiperidine, this compound is a good base but a poor nucleophile which makes it a useful organic reagent.

Hünig's base forms a complex heterocyclic compound called Scorpionine by a reaction with disulfur dichloride catalyzed by DABCO in a remarkable one-pot synthesis.[1]

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