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来源：百度知道 编辑：UC知道 时间：2024/05/17 05:04:19
Alternatives to conventional bone grafts are needed.
Using a degradable polymer/ceramic composite system, our
laboratory has developed porous matrices for use as
trabecular bone graft replacements. Composed of 50:50
poly(lactide-co-glycolide) (PLAGA) and hydroxyapatite
(HA), these matrices possess a three-dimensional (3D), porous
structure based on microsphere technology. Our
current studies examine the relationship between processing
conditions and internal matrix structure. This has led
to the development of three novel processes capable of
fabricating a 3D porous structure: (1) a sintered microsphere
method, (2) a solvent cast microsphere method, and (3) a
gel microsphere method.
Preliminary characterization of matrix structure was
carried out by scanning electron microscopy (SEM). The
solvent cast and sintered microsphere methods used prefabricated
microspheres isolated through a solvent
evaporatio

替代传统的骨移植是必要的。
Using a degradable polymer/ceramic composite system, our使用可降解聚合物/陶瓷复合系统，我们的
laboratory has developed porous matrices for use as实验室开发了多孔矩阵用作
trabecular bone graft replacements.松质骨移植替代品。 Composed of 50:50组成50:50
poly(lactide-co-glycolide) (PLAGA) and hydroxyapatite聚（乳酸共同乙醇酸） （ PLAGA ）和羟基磷灰石
(HA), these matrices possess a three-dimensional (3D), porous （医管局） ，这些矩阵具有三维（三维） ，多孔
structure based on microsphere technology.结构的微球技术。 Our我们的
current studies examine the relationship between processing目前的研究审查之间的关系处理
conditions and internal matrix structure.条件和内部矩阵结构。 This has led这已导致
to the development of three novel processes capable of发展的三个新工艺能力
fabricating a 3D porous structure: (1) a sintered microsphere编造三维多孔结构： （ 1 ）烧结微球
method, (2) a solvent cast microsphere method, and (3) a方法， （ 2 ）溶剂铸球的方法，和（ 3 ）
gel microsphere method.凝胶微球的方法。
Preliminary characterization of matrix structure was初步表征矩阵结构
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