高分求医学类专业翻译！急！！！！！在线等5

来源：百度知道 编辑：UC知道 时间：2024/06/15 01:40:32
Our observation of a “reversal” of the aging signature in skeletal muscle following six months of resistance exercise training is interesting from a number of perspectives. It is well known that resistance exercise training results in an increase in strength, function and muscle mass in younger and older adults，Furthermore, long-term habitual physical activity is associated with a lower risk of age-associated morbidity and mortality. We have previously shown that there is an increase in cytochrome c oxidase activity and a reduction in oxidative stress in older adults after several months of resistance exercise training. To our knowledge, the only other comparable data comes from mice that were inbred for their running capacity and the cardiac muscle transcriptome pattern for older “runners” was more similar to younger animals as compared with the less active older animals and the less active older animals were most different at the level of the mitochondria. It is possible that our obs

我们观察了“逆转”的老龄化签名骨骼肌以下6个月的抵抗运动训练有趣的是从一些观点。众所周知，抵抗运动训练的结果增加了强度，功能和肌肉块在年轻和老年人，此外，长期习惯性的身体活动与风险较低的年龄相关发病率和死亡率。之前我们已经表明，增加细胞色素C氧化酶活性和减少氧化应激的老年人经过几个月的抵抗运动训练。据我们所知，唯一的其他可比较的数据来自于近交系小鼠中的运行能力和心肌转录模式为老年人“运动员”是更接近年轻的动物相比，不那么活跃老年人的动物和较活跃的旧动物最有不同级别的线粒体。这是可能的，我们观察扭转线粒体老化基于签名可以表明，针对运动训练仅仅是由于较低的惯常演习老年人。反对，这是一个事实，即目前的研究是专门设计来避免这一confounder选择健康，积极，无病老年人和比较，他们同样积极的年轻成年人（相对无效的年龄） 。在未来，这将是非常重要，以决定是否长期或终身锻炼可以减轻人类的转录签署老化使用横断面抽样大师运动员。