请帮忙翻译一段话,不胜感激（谢绝机器）

来源：百度知道 编辑：UC知道 时间：2024/06/09 09:09:04
Previous meta-analyses have shown that aspirin is of substantial net benefi t in secondary prevention, but the balance of beneficial effects and bleeding hazards in primary prevention was less clear. The availability of individual participant data for the present meta-analysis has allowed more reliable comparison of the benefits and hazards of aspirin in apparently healthy people. All four of the proportional reductions in major coronary events and in ischaemic stroke in the primary and in the secondary prevention trials were similar to each other (figure 3). Vascular mortality was not signifi cantly reduced in the primary prevention trials, although a proportional reduction comparable with that in the secondary prevention trials could not be excluded. Whether or not the proportional benefits are similar, however, the absolute benefits of aspirin are an order of magnitude smaller in the primary than in the secondary prevention trials (table 2

先前的荟萃分析显示阿司匹林是可观的净benefi二级预防,但不平衡的作用,beneficial出血灾害预防不太明显。个别的荟萃分析的数据,目前已允许更可靠的benefits比较明显的阿斯匹林的特点及其危害健康的人。所有的四种主要的冠心病事件的比例下降,在缺血性卒中患者在小学和中学预防试验是相似的figure(3)。没有significantly血管的死亡率下降的主要防治试验,尽管有相当比例下降和二级预防试验将不会被排除在外。是否有类似的比例benefits,然而,绝对benefits的阿司匹林在数量级较小的主要比二级预防试验(表2)。(我们忽略了假设的最终减少癌症死亡率,因为它预计会有什么影响进行分析的基础上,对我们的计划在治疗期间死亡

前荟萃分析表明，阿司匹林是大量有益的T净二级预防，但如何平衡有益的影响和危害的出血初级预防是不太清楚。提供个别参与者数据本Meta分析使得更可靠的比较利益和危险的阿司匹林在看起来健康的人。所有四个比例减少主要冠脉事件和缺血性中风的初级和二级预防试验，类似彼此（图3 ） 。血管死亡率没有显着减少，初级预防试验中，虽然比例减少媲美，在二级预防试验不能被排除在外。不管比例的好处是相似的，但是，绝对好处阿司匹林是一个数量级较小的初级比二级预防试验（表2 ） 。 （我们忽略了假设最终