difference的问题呢

你是问difference of和difference in的用法吗？
例句
what is the difference of a and b
他们有什么差别
what is the difference in a and b
他们里面有什么不同
其实含义都一样,只看你的用法，要学用法只有多接触英文

different adj.
不同的 各别的, 差异的 [常作表语]
as different again 又大不相同(指向好处转变的差异) as different as chalk from cheese (尽管外表相似)本质上完全不同
be different from 与...不同
be different to 与...不同
be different than 与...不同

The two boys are different in their tastes.
这两个男孩的兴趣是相异的。
I don't like that dress, I want a different one.
我不喜欢那套衣服，我想要一件不同（样式）的。
It was very different from modern car races but no less exciting.
"它与现代小汽车比赛大不相同,但激动人心的程度却毫不逊色。"
Susan is different from / than / to Alice.
苏姗和爱丽丝不同。

difference n.
all the difference (in the world) 天渊之别, 大不相同
as near as makes no difference 没有多少差别
iron out the difference(s) 消除分歧
make a great difference 有很大差别, 有很大 不同 有很大的关系[影响]
make a difference