UC知道我有一篇英文化学论文 想找英语高手帮忙翻译
来源：百度知道 编辑：UC知道 时间：2024/05/15 16:01:47
The most widely used 1O2 trap is 9,10-diphenylanthracene (DPA), which reacts rapidly and
specifically with 1O2 to form a thermostable endoperoxide at a rate of k =1.3106 M1 s1.
The decrease in absorbance at 355 nm is used as a measure of the formation of the endoperoxide.
However, DPA derivatives are not very sensitive probes because the detection is based on the
measurement of absorbance [79].
Umezaka et al. [79] fused DPA with a fluorophore (fluorescein) aiming to associate the first’s
reactive characteristics with the second’s fluorescent characteristics. Fluorescein was chosen as
fluorophore since it has a high fluorescence quantum yield in aqueous solution and is able to be
excited at long wavelength. From this fusion resulted 9-[2-(3-carboxy-9,10-diphenyl)anthryl]-6-
hydroxy-3H-xanthen-3-ones (DPAXs) (Fig. 11) [79]. Thus, DPAXs were the first chemic
420. 91-[2-(3-羧基-9,10-二苯)anthryl]-6 羟基3h-xanthen-3-酮 (dpaxs)使用最广泛的1o2阱9,10-diphenylanthracene(政治部) 而迅速的反应,特别是与1o2形成耐热endoperoxide的增长率为k=1.3106米1秒1. 减少24.6%,为355nm,是用来衡量形成的过氧化物. 不过,政治部衍生不是很敏感的探针,因为检测是基于测量吸光度[79]. umezakaetal. [79]fused审批与fluorophore(fluorescein)以准第一功的特点与第二的荧光特性. fluorescein被选为fluorophore,因为它具有较高的荧光量子产率在水溶液中,并能 兴奋长波长. 由此导致的融合 91-[2-(3-羧基-9,10-二苯)anthryl]-6 - 羟基3h-xanthen-3酮(dpaxs)(图11)[79]. 因此,dpaxs被化学第一陷阱1o2允许荧光检测. 他们的反应与1o2出示dpaxendoperoxides(dpax-eps)(图11). dpaxs自己scarcelyfluoresce,而dpaxeps强烈的荧光. 机制的会计核算窄化荧光dpaxs及其增强dpax-办事仍不清楚[79]. 荧光强度的荧光素衍生物已知是减少酸性条件下,随着大量的质子 该phenoxide氧原子. 为了稳定的荧光强度,在生理pH, 电子撤组wereincorporated在2-和7点位置的xanthene生色 通往cl(dpax-2)和F(dpax-3)(图11). 这个修改降低pKa值的酚氧原子〔79〕. dpax-2检测生产1o2从两个不同的发电系统: 该moo42/过氧化氢体系和3-(4-甲基-1-萘基)丙酸endoperoxide(ep-1)系统, 该法在不同pH值(10.5和7.4美元). 在这两种情况下,提高了探头的荧光验证时接触的发电系统. 这些调查结果证实dpaxs的优势,在检测1o2在中性或碱性溶液[79]. 该行为此探针对双氧水,! NO和O2! 还研究, 但不改变强度的荧光染色任何这些活性物种. 这些事实证实特异性这种探针1o2[79]. 检测1o2生物样品中为2.75%. 为了这个目的,dpax-2diacetate(dpax-2-da)制成的,因为