What's the throuble with you?

What's the trouble with you?是正确的

不是很对。
有以下比较相近的几种说法：
1.What troubles you?
2.What's the trouble?
3.What's the matter with you?

what's giving you trouble

trouble，拼写错误

throuble，拼写错了，应该是trouble。

What's the trouble with you?