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Targeting a specific allele with similar models, RNAi can be used to remove the source of alleles to meet with transgenic substitute purposes. Equivalent method against this heavy-untranslated region MRNA the DSRNA with the ability to inhibit gene expression. This does not require coding sequence can be removed targeting endogenous gene expression. allele due to the lack of a breakthrough role without targeting endogenous wild-type allele effects.
In a related way, with an epitope tagged as the gene can be targeted through non-untranslated region and the lack of endogenous protein expression in cells expression. As this method has the potential of proteomics research tools value. out if, in the way the term has been the lack of endogenous Drosophila outside body (exosome) component of RRP4, while the homologous gene into human allele with labels, it will greatly promote the labeling protein-doped mention of the endogenous protein complexes efficiency. directly address label af