急求谁能帮忙翻译下4

来源:百度知道 编辑:UC知道 时间:2024/06/18 15:40:48
The homeostasis of hepatic microcirculatory environment is crucial for the early recovery of graft function after reperfusion. 28 The liver sinusoids play an important role in hepatic microcirculation, especially at the early phase after reperfusion. Due to a combination of a higher portal pressure and sinusoidal constriction induced by an imbalance of vasoregulatory genes at the acute phase after reperfusion, the hepatic sinusoidal lining cells are disrupted. The injured hepatic sinusoids thus impair recovery of hepatic synthetic function, which is reflected by the lower expression of heat shock proteins.
The understanding of the mechanism of small-for-size graft injury not only is helpful to develop novel therapeutic strategies to reduce small-for-size graft damage to the recipient, but also prevents small-for-size syndrome of living donors after a right lobe liver donation. To avoid the small-for-size graft injury, several methods such as splenic artery ligation 29 and portocav

稳态肝微循环障碍的环境是极为重要的,为他们早日康复,移植肾功能后,再灌注。 28肝血窦中发挥了重要作用,在肝脏微循环,尤其是在初期阶段后,再灌注。原因有多种较高的门静脉压力和正弦收缩所致不平衡vasoregulatory基因在急性期再灌注后,肝窦内衬细胞受到破坏。伤者肝血窦,从而妨碍复苏的肝脏合成功能,这反映在较低的热休克蛋白的表达。
该机理的认识小体积移植物损伤,不仅有利于开发新的治疗策略,以减低小体积移植物的损害向受赠人,而且也可防止小体积综合征的活体供者后,有权叶肝脏捐赠。为了避免小体积移植物损伤,几种方法,如脾动脉结扎29和portocaval调30个已应用于衰减门脉高压灌注后。逐步控制释放的门静脉钳上的时候,再灌注可能有助于改善不良的影响,大量的血液流入肝脏,但其实际效果尚不得而知。
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