急!求这个医学论文片段的英文翻译

来源:百度知道 编辑:UC知道 时间:2024/06/23 04:14:21
用鼠耳肿胀模型验证糖皮质激素、阿司匹林、对乙酰氨基酚的抗炎作用
实验目的:
1.观察糖皮质激素,阿司匹林,对乙酰氨基酚的抗炎症作用
2.比较糖皮质激素与阿司匹林,阿司匹林与对乙酰氨基酚的抗炎症作用
实验原理:
利用动物实验性炎症模型可以观察抗炎药物的作用。将二甲苯涂于小鼠耳部(注射可能损伤过大,导致氢化可的松的作用显示不出来),可致局部细胞损伤,使某些炎性物质如组胺、缓激肽和纤维蛋白溶酶等释放,引起局部毛细血管通透性增强,炎症细胞浸润,造成耳部急性渗出型炎性水肿。根据致炎一侧耳与另一侧耳的重量差,可计算肿胀度。对给药组与对照组肿胀度进行差异比较,可定性确定药物的抗炎作用。

利用二甲苯的致炎作用,将小鼠一侧耳朵致炎,另一侧作为对照。比较两耳的质量差别
请各位不要随便拿个答案来误导人 谢谢
如果谷歌和金山就可以翻译了 我就不用贴到这来了

Using mouse ear swelling model verification glucocorticoid, aspirin, acetaminophen anti-inflammatory effect
The purpose of the experiment:
1. Glucocorticoid observation, aspirin, acetaminophen role in the anti-inflammatory
2. Glucocorticoid compared with aspirin, aspirin and acetaminophen the anti-inflammatory effect
Experimental principle:
The use of animal experimental model of inflammatory anti-inflammatory drugs can be observed. Xylene will be applied to mouse ears (injection may be too much damage, leading to the role of hydrocortisone did not show up) can be addressed to the local cell injury, certain inflammatory substances such as histamine, bradykinin and fiber The release of soluble protein enzymes, causing local vascular permeability increased infiltration of inflammatory cells, resulting in acute ear effusion-inflammatory edema. According to one ear inflammation caused by ear with a weight difference can be calculated swelling degrees. On th