医学资料翻译!~急!

来源:百度知道 编辑:UC知道 时间:2024/06/24 10:55:14
10. Chung发现在肝细胞癌(HCC)中, eIF4A的表
达量上升了1.2~1.7倍。eIF4A作为eIF4F复合物中
的解旋酶成分,可直接行使解开5′UTR二级结构功能
并导致多种具有复杂二级结构的5′UTR的调控蛋白表
达量的上升,如FGFR-1、FGFR-2和FGFR-4等,从而产
生癌变表型。
EIF4A控制着翻译起始,是细胞增生和癌变的一个关键点,研
究发现该基因在人黑色素瘤细胞中持续高表达, 将其
反义重组子转染至黑色素细胞中,细胞的增生能力明
显降低
翻译软件做的汉译英就不用麻烦了,句子不通顺的。
费心翻译一下,谢谢!

In hepatic cellular cancer (HCC), Chung reports that expression amount of eIF4A rises up by 1.2~1.7 times. eIF4A, as a helicase component of eIF4F complex, can directly unwide the secondary structure of the 5’-untranslated region (5’-UTR) and make expression amount of some modulin upgrade, which has complicated secondary structure of 5’-UTR, such as FGFR-1、FGFR-2 and FGFR-4 and so on, and then induce phenotype of carcinomatous change.

EIF4A controls the initiation of translation that is a key to cellular proliferation and carcinomatous change. It is reported that EIF4A expresses persistently and highly in human melanoma cells, and make its antisense recon transfect into the melanoma cells, then the proliferation of cells is obviously degraded.

10. this cooperation found in hepatocellular carcinoma (HCC), eIF4A tables
The amount of $ rose by 1.2 ~ 1.7 times.EIF4A as eIF4F complex
Of helicase components, you can direct the exercise of untied the 5 ' UTR