翻译专业英语(分子生物学)

来源：百度知道 编辑：UC知道 时间：2024/05/14 10:01:20
Methylation of promoter-CpG islands can result in transcriptional silencing of genes through a number of mechanisms, including (i) prevention of methylation-sensitive transcription factor binding and (ii) attraction of methyl-cytosine proteins that interact with histone deacetylases (HDACs) and chromatin remodelling factors leading to chromatin condensation and an inaccessibility of the promoter to transcription factors .

甲基化启动子CpG岛可导致基因转录沉默通过若干机制包括(一)预防甲基敏感转录因子结合(二)吸引力甲基胞嘧啶蛋白质相互作用及染色质蛋白去乙酰(hdacs)重塑因素导致染色及科目为启动转录因子.