UC知道急寻英语高手翻译生命科学论文
来源：百度知道 编辑：UC知道 时间：2024/05/10 16:55:00
It appears that for some normal cell types exogenous
hTERT is not sufficient for extension of proliferative lifespan (Table 1). In human keratinocytes, expression of
hTERT was ineffective in the absence of HPV16 E7
expression [30••]. A similar phenomenon was also detect-
ed in normal breast epithelial cells that commonly exhibit
extended in vitro growth potential associated with sponta-
neously downregulated expression of the p16INK4agene
due to DNA methylation [31–33]. Exogenous hTERT had
no effect unless p16INK4aexpression was downregulated([30••]; C Toouli, L Huschtscha, RR Reddel, unpublisheddata). These studies point to the possibility that additional changes, such as inactivation of the pRb/p16INK4apathway, are a pre-requisite for hTERT-induced increase
in proliferative potential.
找一些翻译软件翻译的请不要写了。
难道没有高手了？
hTERT is not sufficient for extension of proliferative lifespan (Table 1). In human keratinocytes, expression of
hTERT was ineffective in the absence of HPV16 E7
expression [30••]. A similar phenomenon was also detect-
ed in normal breast epithelial cells that commonly exhibit
extended in vitro growth potential associated with sponta-
neously downregulated expression of the p16INK4agene
due to DNA methylation [31–33]. Exogenous hTERT had
no effect unless p16INK4aexpression was downregulated([30••]; C Toouli, L Huschtscha, RR Reddel, unpublisheddata). These studies point to the possibility that additional changes, such as inactivation of the pRb/p16INK4apathway, are a pre-requisite for hTERT-induced increase
in proliferative potential.
找一些翻译软件翻译的请不要写了。
难道没有高手了？
看来一些正常细胞类型外部 hTERT不足增殖寿命延长(见表1). keratinocytes人,表达 hTERT是无效没有HPV16E7 发表30--). 也发现了类似的现象. 32正常乳房上皮细胞共同展出 将试管sponta与发展潜力. neouslydownregulated发表的P16ink4agene 由于DNA甲基化31496). 外界有hTERT 如果是无效p16ink4aexpressiondownregulated(30--); CToouli,HuschtschaL,ReddelRR,Unpublisheddata. 研究表明,可能有更多的变化,如肿瘤的Prb/p16ink4apathway,先决条件hTERT引起增加 增殖的潜力.
....楼上的用机器啊~还有没翻译的呢