UC知道谁能帮我专业的翻译这段话,请教,急用
来源：百度知道 编辑：UC知道 时间：2024/04/30 05:51:04
The development of a LC–MS/MS analytical method for digoxin for
the P-gp inhibition assay has several other advantages: potential
ease-of-transfer of the assay for higher throughput applications,
only digoxin is being monitored thus the LC–MS/MS assay can
be run continuously without optimizing for new compounds,
there are no analytical issues associated with metabolism (i.e.
degradation of digoxin) or tritium–water exchange. Thus, the
specificity ofMS/MSdetection using tandem mass spectrometry
affords an attractive alternative to eliminate the use of radioactive isotopes in this P-gp inhibition assay while providing high sensitivity
the P-gp inhibition assay has several other advantages: potential
ease-of-transfer of the assay for higher throughput applications,
only digoxin is being monitored thus the LC–MS/MS assay can
be run continuously without optimizing for new compounds,
there are no analytical issues associated with metabolism (i.e.
degradation of digoxin) or tritium–water exchange. Thus, the
specificity ofMS/MSdetection using tandem mass spectrometry
affords an attractive alternative to eliminate the use of radioactive isotopes in this P-gp inhibition assay while providing high sensitivity
发展一个lc-ms/ms分析方法地高辛为
有关P糖蛋白抑制法有几个其他的优点：潜力
易用性转移的检测为高吞吐量的应用，
只有地高辛正被监视的，因此可以测定lc-ms/ms
运行不断优化，没有为新化合物，
有没有分析相关的问题与代谢（即
退化地高辛）或氚-水交换。因此，
特异性ofms / msdetection使用串联质谱
提供了一个有吸引力的替代性，以消除使用放射性的同位素在这P糖蛋白抑制法，同时提供高灵敏度